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BDBM50414540 CHEMBL562692

SMILES: Cc1cc(C)c(-c2nnc(NC(=O)c3ccc4OCCc4c3)s2)c(C)c1

InChI Key: InChIKey=LOUALGVBZHIPTI-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414540   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor


(Homo sapiens (Human))		BDBM50414540
PNG
(CHEMBL562692)
Show SMILES Cc1cc(C)c(-c2nnc(NC(=O)c3ccc4OCCc4c3)s2)c(C)c1
Show InChI InChI=1S/C20H19N3O2S/c1-11-8-12(2)17(13(3)9-11)19-22-23-20(26-19)21-18(24)15-4-5-16-14(10-15)6-7-25-16/h4-5,8-10H,6-7H2,1-3H3,(H,21,23,24)
PDB

KEGG

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PC cid
PC sid
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 200n/an/an/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assay

Bioorg Med Chem Lett 19: 4292-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.05.074
BindingDB Entry DOI: 10.7270/Q2SQ90DS
More data for this
Ligand-Target Pair