BDBM50414712 CHEMBL565146

SMILES: [H][C@@]12CC[C@]([H])(CC(C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCN1CCN(CC1)S(C)(=O)=O

InChI Key: InChIKey=MEVLETXNRMDOKR-DHIUTWEWSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414712 (CHEMBL565146) Show SMILES [H][C@@]12CC[C@]([H])(CC(C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCN1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C27H39N5O4S/c1-19(2)32-25-7-5-4-6-20(25)16-24(27(32)34)26(33)28-21-17-22-8-9-23(18-21)31(22)15-12-29-10-13-30(14-11-29)37(3,35)36/h4-7,16,19,21-23H,8-15,17-18H2,1-3H3,(H,28,33)/t22-,23-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50414712 (CHEMBL565146) Show SMILES [H][C@@]12CC[C@]([H])(CC(C1)NC(=O)c1cc3ccccc3n(C(C)C)c1=O)N2CCN1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C27H39N5O4S/c1-19(2)32-25-7-5-4-6-20(25)16-24(27(32)34)26(33)28-21-17-22-8-9-23(18-21)31(22)15-12-29-10-13-30(14-11-29)37(3,35)36/h4-7,16,19,21-23H,8-15,17-18H2,1-3H3,(H,28,33)/t22-,23-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31	n/a	n/a	n/a	n/a
Theravance, Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assay				J Med Chem 52: 5330-43 (2009) Article DOI: 10.1021/jm900881j BindingDB Entry DOI: 10.7270/Q2CF9RBH
					More data for this Ligand-Target Pair