BDBM50414756 CHEMBL569201

SMILES: CCOc1ccccc1N1CCN(CC(O)CN2CCC(C2=O)(c2ccccc2)c2ccccc2)CC1

InChI Key: InChIKey=XNFQPXDAESFNLR-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50414756 (CHEMBL569201) Show SMILES CCOc1ccccc1N1CCN(CC(O)CN2CCC(C2=O)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O3/c1-2-37-29-16-10-9-15-28(29)33-21-19-32(20-22-33)23-27(35)24-34-18-17-31(30(34)36,25-11-5-3-6-12-25)26-13-7-4-8-14-26/h3-16,27,35H,2,17-24H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	281	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at Alpha-1B adrenoceptor in guinea pig spleen assessed as inhibition of noradrenaline-induced contraction after 30 mins				Eur J Med Chem 44: 3994-4003 (2009) Article DOI: 10.1016/j.ejmech.2009.04.028 BindingDB Entry DOI: 10.7270/Q23X87WF
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50414756 (CHEMBL569201) Show SMILES CCOc1ccccc1N1CCN(CC(O)CN2CCC(C2=O)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O3/c1-2-37-29-16-10-9-15-28(29)33-21-19-32(20-22-33)23-27(35)24-34-18-17-31(30(34)36,25-11-5-3-6-12-25)26-13-7-4-8-14-26/h3-16,27,35H,2,17-24H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	55.0	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at Alpha-1D adrenoceptor in Wistar rat thoracic aorta assessed as inhibition of noradrenaline-induced contraction after 30 mins				Eur J Med Chem 44: 3994-4003 (2009) Article DOI: 10.1016/j.ejmech.2009.04.028 BindingDB Entry DOI: 10.7270/Q23X87WF
					More data for this Ligand-Target Pair