BDBM50415241 CHEMBL595549

SMILES: CCn1nccc1NC1C(=NNc2c(C)cc(cc12)S(=O)(=O)CC)C(N)=O

InChI Key: InChIKey=HUQIRFTVRSLJPN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50415241 (CHEMBL595549) Show SMILES CCn1nccc1NC1C(=NNc2c(C)cc(cc12)S(=O)(=O)CC)C(N)=O |c:10| Show InChI InChI=1S/C17H22N6O3S/c1-4-23-13(6-7-19-23)20-15-12-9-11(27(25,26)5-2)8-10(3)14(12)21-22-16(15)17(18)24/h6-9,15,20-21H,4-5H2,1-3H3,(H2,18,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain by scintillation proximity assay				Bioorg Med Chem Lett 20: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.11.010 BindingDB Entry DOI: 10.7270/Q2RJ4KPG
					More data for this Ligand-Target Pair