BDBM50415369 CHEMBL601449

SMILES: CN(C(=O)c1c(C)onc1-c1ccccc1Cl)c1ccc(F)cc1

InChI Key: InChIKey=JBUPMTYOVUGFHY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled bile acid receptor 1 (Homo sapiens (Human))	BDBM50415369 (CHEMBL601449) Show SMILES CN(C(=O)c1c(C)onc1-c1ccccc1Cl)c1ccc(F)cc1 Show InChI InChI=1S/C18H14ClFN2O2/c1-11-16(17(21-24-11)14-5-3-4-6-15(14)19)18(23)22(2)13-9-7-12(20)8-10-13/h3-10H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...				Bioorg Med Chem Lett 20: 1363-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.003 BindingDB Entry DOI: 10.7270/Q2028SS5
					More data for this Ligand-Target Pair