BDBM50415424 CHEMBL601638

SMILES: CN(C(=O)c1c(onc1-c1ccccc1Cl)C1CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=GTKLSYNDCZPIOK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled bile acid receptor 1 (Homo sapiens (Human))	BDBM50415424 (CHEMBL601638) Show SMILES CN(C(=O)c1c(onc1-c1ccccc1Cl)C1CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H16Cl2N2O2/c1-24(14-10-8-13(21)9-11-14)20(25)17-18(15-4-2-3-5-16(15)22)23-26-19(17)12-6-7-12/h2-5,8-12H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.98	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human TGR5 receptor expressed in human U2-OS cells assessed as changes in response to cAMP level by MRE/CRE-driven luciferase rep...				Bioorg Med Chem Lett 20: 1363-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.003 BindingDB Entry DOI: 10.7270/Q2028SS5
					More data for this Ligand-Target Pair