BDBM50415623 CHEMBL1087810

SMILES: CCC1=NCCc2cc(OC)c(Cl)cc12

InChI Key: InChIKey=PMRDGUOYVKCWKU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50415623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50415623 (CHEMBL1087810) Show SMILES CCC1=NCCc2cc(OC)c(Cl)cc12 |t:2| Show InChI InChI=1S/C12H14ClNO/c1-3-11-9-7-10(13)12(15-2)6-8(9)4-5-14-11/h6-7H,3-5H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropy				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50415623 (CHEMBL1087810) Show SMILES CCC1=NCCc2cc(OC)c(Cl)cc12 |t:2| Show InChI InChI=1S/C12H14ClNO/c1-3-11-9-7-10(13)12(15-2)6-8(9)4-5-14-11/h6-7H,3-5H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropy				Bioorg Med Chem Lett 19: 2230-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.098 BindingDB Entry DOI: 10.7270/Q2Z320WR
					More data for this Ligand-Target Pair