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SMILES: Cc1nn(C)c2ncc(C(=O)NCc3ccc(Cl)c(c3)C(F)(F)F)c(Cl)c12

InChI Key: InChIKey=GOGQOBHFDBPZLG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415789   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415789
PNG
(CHEMBL1093773)
Show SMILES Cc1nn(C)c2ncc(C(=O)NCc3ccc(Cl)c(c3)C(F)(F)F)c(Cl)c12
Show InChI InChI=1S/C17H13Cl2F3N4O/c1-8-13-14(19)10(7-23-15(13)26(2)25-8)16(27)24-6-9-3-4-12(18)11(5-9)17(20,21)22/h3-5,7H,6H2,1-2H3,(H,24,27)
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Similars
Article
PubMed
n/an/a 63.1n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair