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SMILES: Cc1nn(C)c2ncc(C(=O)NCc3ccccn3)c(Cl)c12

InChI Key: InChIKey=ICQNSTSOTOXDQL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50415802   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415802
PNG
(CHEMBL1089707)
Show SMILES Cc1nn(C)c2ncc(C(=O)NCc3ccccn3)c(Cl)c12
Show InChI InChI=1S/C15H14ClN5O/c1-9-12-13(16)11(8-18-14(12)21(2)20-9)15(22)19-7-10-5-3-4-6-17-10/h3-6,8H,7H2,1-2H3,(H,19,22)
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Similars
Article
PubMed
n/an/a>6.31E+3n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair