BDBM50416280 CHEMBL1170187

SMILES: Clc1cnc(Oc2cccnn2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1

InChI Key: InChIKey=YGRSQZLQJVIMGG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416280 (CHEMBL1170187) Show SMILES Clc1cnc(Oc2cccnn2)c(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C15H9Cl3N4O3S/c16-9-6-13(15(19-8-9)25-14-2-1-5-20-21-14)22-26(23,24)10-3-4-11(17)12(18)7-10/h1-8,22H	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 expressed in CHO cells assessed as inhibition of MCP1-induced [35S]-GTPgammaS binding after 3 hrs				Bioorg Med Chem Lett 20: 3961-4 (2010) Article DOI: 10.1016/j.bmcl.2010.04.142 BindingDB Entry DOI: 10.7270/Q2B56KZ9
					More data for this Ligand-Target Pair