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BDBM50416355 CHEMBL1172407

SMILES: COc1cccc2C(=O)N(C)C(CCN(C)C)(Cc12)c1ccc(Cl)cc1

InChI Key: InChIKey=NBJNYWWBLPKFAW-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416355   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urotensin-2


(Homo sapiens (Human))		BDBM50416355
PNG
(CHEMBL1172407)
Show SMILES COc1cccc2C(=O)N(C)C(CCN(C)C)(Cc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H25ClN2O2/c1-23(2)13-12-21(15-8-10-16(22)11-9-15)14-18-17(20(25)24(21)3)6-5-7-19(18)26-4/h5-11H,12-14H2,1-4H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.17E+3n/an/an/an/a



University of Gothenburg

Curated by ChEMBL


Assay Description
Agonist activity against human urotensin 2 receptor expressed in human NIH373 cells assessed as beta-galactosidase activity after 5 days by R-SAT ass...

Bioorg Med Chem 18: 4844-54 (2011)


Article DOI: 10.1016/j.bmc.2010.04.041
BindingDB Entry DOI: 10.7270/Q2PG1SZ3
More data for this
Ligand-Target Pair