BDBM50416368 CHEMBL1210603

SMILES: COC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=PKLYBOYMHPUXHN-MHZLTWQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50416368 (CHEMBL1210603) Show SMILES COC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CCc1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C29H25Cl2N5O3/c1-39-29(38)27(14-23-16-32-17-33-23)34-28(37)9-8-25-15-26(20-10-21(30)13-22(31)11-20)35-36(25)24-7-6-18-4-2-3-5-19(18)12-24/h2-7,10-13,15-17,27H,8-9,14H2,1H3,(H,32,33)(H,34,37)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of CCR2				Eur J Med Chem 45: 3394-406 (2010) Article DOI: 10.1016/j.ejmech.2010.04.024 BindingDB Entry DOI: 10.7270/Q2JQ1275
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