BDBM50416386 CHEMBL1210500

SMILES: Cc1noc(C)c1CCC(=O)NCc1ccc(F)cc1Cl

InChI Key: InChIKey=LTAXMLURRKBEHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416386 (CHEMBL1210500) Show SMILES Cc1noc(C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C15H16ClFN2O2/c1-9-13(10(2)21-19-9)5-6-15(20)18-8-11-3-4-12(17)7-14(11)16/h3-4,7H,5-6,8H2,1-2H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair