BDBM50416387 CHEMBL1210499

SMILES: Cc1cc(CCC(=O)NCc2ccc(F)cc2Cl)n(C)n1

InChI Key: InChIKey=IEOCQFNGSKTTLW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416387 (CHEMBL1210499) Show SMILES Cc1cc(CCC(=O)NCc2ccc(F)cc2Cl)n(C)n1 Show InChI InChI=1S/C15H17ClFN3O/c1-10-7-13(20(2)19-10)5-6-15(21)18-9-11-3-4-12(17)8-14(11)16/h3-4,7-8H,5-6,9H2,1-2H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair