BDBM50416393 CHEMBL1210436

SMILES: CC(C)Cc1n[nH]c(C)c1CCC(=O)NCc1ccc(F)cc1Cl

InChI Key: InChIKey=WHBHNUPGTZWXHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416393 (CHEMBL1210436) Show SMILES CC(C)Cc1n[nH]c(C)c1CCC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C18H23ClFN3O/c1-11(2)8-17-15(12(3)22-23-17)6-7-18(24)21-10-13-4-5-14(20)9-16(13)19/h4-5,9,11H,6-8,10H2,1-3H3,(H,21,24)(H,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor ethidium bromide release assay				Bioorg Med Chem Lett 20: 4653-6 (2010) Article DOI: 10.1016/j.bmcl.2010.05.107 BindingDB Entry DOI: 10.7270/Q2DZ09HF
					More data for this Ligand-Target Pair