BDBM50416600 CHEMBL1222823

SMILES: CC(=O)N1CCC[C@H]1C(=O)NCc1ccc(F)cc1Cl

InChI Key: InChIKey=ZRZPERAMNKYGAE-ZDUSSCGKSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416600 (CHEMBL1222823) Show SMILES CC(=O)N1CCC[C@H]1C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C14H16ClFN2O2/c1-9(19)18-6-2-3-13(18)14(20)17-8-10-4-5-11(16)7-12(10)15/h4-5,7,13H,2-3,6,8H2,1H3,(H,17,20)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay				Bioorg Med Chem Lett 20: 5080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T
					More data for this Ligand-Target Pair