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BDBM50416886 CHEMBL1256486

SMILES: CC(c1nc2ccccc2s1)c1ccc(C)cc1C

InChI Key: InChIKey=KDVGSNNINKOFHY-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50416886
PNG
(CHEMBL1256486)
Show SMILES CC(c1nc2ccccc2s1)c1ccc(C)cc1C
Show InChI InChI=1S/C17H17NS/c1-11-8-9-14(12(2)10-11)13(3)17-18-15-6-4-5-7-16(15)19-17/h4-10,13H,1-3H3
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.51E+3n/an/an/an/a



ACADIA Pharmaceuticals AB

Curated by ChEMBL


Assay Description
Positive allosteric modulation of calcium sensing receptor by cell based assay


Bioorg Med Chem Lett 20: 5918-21 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.077
BindingDB Entry DOI: 10.7270/Q22J6D4S
More data for this
Ligand-Target Pair