BDBM50416932 CHEMBL1258860

SMILES: CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(OCc3ccccc3)cc2)n1

InChI Key: InChIKey=ZMNMQJJTADRAMG-SANMLTNESA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50416932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50416932 (CHEMBL1258860) Show SMILES CCSc1nnc-2c(O[C@H](N(C(C)=O)c3ccccc-23)c2ccc(OCc3ccccc3)cc2)n1 |r| Show InChI InChI=1S/C27H24N4O3S/c1-3-35-27-28-25-24(29-30-27)22-11-7-8-12-23(22)31(18(2)32)26(34-25)20-13-15-21(16-14-20)33-17-19-9-5-4-6-10-19/h4-16,26H,3,17H2,1-2H3/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Inhibition of rat mGluR1 expressed in HEK293 cells				Bioorg Med Chem Lett 20: 5922-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.061 BindingDB Entry DOI: 10.7270/Q2XS5WN3
					More data for this Ligand-Target Pair