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SMILES: OC(=O)C1CCN(CC1)C1CCC2(C1)c1ccccc1Sc1ccc(F)cc1C2=O

InChI Key: InChIKey=GSUXFSXZSCBDQK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))		BDBM50417356
PNG
(CHEMBL1277491)
Show SMILES OC(=O)C1CCN(CC1)C1CCC2(C1)c1ccccc1Sc1ccc(F)cc1C2=O
Show InChI InChI=1S/C24H24FNO3S/c25-16-5-6-20-18(13-16)22(27)24(19-3-1-2-4-21(19)30-20)10-7-17(14-24)26-11-8-15(9-12-26)23(28)29/h1-6,13,15,17H,7-12,14H2,(H,28,29)
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 200n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay

J Med Chem 53: 7778-95 (2010)


Article DOI: 10.1021/jm100856p
BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
More data for this
Ligand-Target Pair