BDBM50417358 CHEMBL1277311

SMILES: OC(=O)[C@@H]1CCCN(C1)C1CCC2(C1)Cc1ccccc1Oc1ccccc21

InChI Key: InChIKey=IQNSUCJNGFOYPQ-JNDNBTNTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50417358 (CHEMBL1277311) Show SMILES OC(=O)[C@@H]1CCCN(C1)C1CCC2(C1)Cc1ccccc1Oc1ccccc21 |r| Show InChI InChI=1S/C24H27NO3/c26-23(27)18-7-5-13-25(16-18)19-11-12-24(15-19)14-17-6-1-3-9-21(17)28-22-10-4-2-8-20(22)24/h1-4,6,8-10,18-19H,5,7,11-16H2,(H,26,27)/t18-,19?,24?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay				J Med Chem 53: 7778-95 (2010) Article DOI: 10.1021/jm100856p BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
					More data for this Ligand-Target Pair