BDBM50417369 CHEMBL1277584

SMILES: OC(=O)[C@@H]1CCCN(C1)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21

InChI Key: InChIKey=GJQONOYIKURBSD-IYRGYZHQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50417369 (CHEMBL1277584) Show SMILES OC(=O)[C@@H]1CCCN(C1)C1CC[C@@]2(C1)Cc1ccccc1Cc1ccccc21 |r| Show InChI InChI=1S/C25H29NO2/c27-24(28)21-9-5-13-26(17-21)22-11-12-25(16-22)15-20-8-2-1-6-18(20)14-19-7-3-4-10-23(19)25/h1-4,6-8,10,21-22H,5,9,11-17H2,(H,27,28)/t21-,22?,25+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay				J Med Chem 53: 7778-95 (2010) Article DOI: 10.1021/jm100856p BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
					More data for this Ligand-Target Pair