BDBM50417370 CHEMBL1277585

SMILES: OC(=O)CC1CCN(CC1)C1CCC2(C1)Cc1ccccc1Cc1ccccc21

InChI Key: InChIKey=XNPQDIOALLTRKK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50417370 (CHEMBL1277585) Show SMILES OC(=O)CC1CCN(CC1)C1CCC2(C1)Cc1ccccc1Cc1ccccc21 Show InChI InChI=1S/C26H31NO2/c28-25(29)15-19-10-13-27(14-11-19)23-9-12-26(18-23)17-22-7-2-1-5-20(22)16-21-6-3-4-8-24(21)26/h1-8,19,23H,9-18H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assay				J Med Chem 53: 7778-95 (2010) Article DOI: 10.1021/jm100856p BindingDB Entry DOI: 10.7270/Q2FQ9WWQ
					More data for this Ligand-Target Pair