null

SMILES: COc1ccc(F)cc1-c1ccc(cc1)[C@@H](C)NS(=O)(=O)c1cn(C)nc1C(F)(F)F

InChI Key: InChIKey=PMGZKXGKJZFMFP-GFCCVEGCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50417607 (CHEMBL1645401) Show SMILES COc1ccc(F)cc1-c1ccc(cc1)[C@@H](C)NS(=O)(=O)c1cn(C)nc1C(F)(F)F |r| Show InChI InChI=1S/C20H19F4N3O3S/c1-12(26-31(28,29)18-11-27(2)25-19(18)20(22,23)24)13-4-6-14(7-5-13)16-10-15(21)8-9-17(16)30-3/h4-12,26H,1-3H3/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.98	n/a	n/a	n/a	n/a
Merck Research Laboratories (MSD) Curated by ChEMBL					Assay Description Binding affinity to human recombinant GR by competition ligand binding fluorescence polarization assay				Bioorg Med Chem Lett 21: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2010.11.054 BindingDB Entry DOI: 10.7270/Q2FN17F9
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50417607 (CHEMBL1645401) Show SMILES COc1ccc(F)cc1-c1ccc(cc1)[C@@H](C)NS(=O)(=O)c1cn(C)nc1C(F)(F)F |r| Show InChI InChI=1S/C20H19F4N3O3S/c1-12(26-31(28,29)18-11-27(2)25-19(18)20(22,23)24)13-4-6-14(7-5-13)16-10-15(21)8-9-17(16)30-3/h4-12,26H,1-3H3/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Merck Research Laboratories (MSD) Curated by ChEMBL					Assay Description Binding affinity to human recombinant PR by competition ligand binding fluorescence polarization assay				Bioorg Med Chem Lett 21: 137-40 (2010) Article DOI: 10.1016/j.bmcl.2010.11.054 BindingDB Entry DOI: 10.7270/Q2FN17F9
					More data for this Ligand-Target Pair