BDBM50417726 CHEMBL1644212

SMILES: COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cccc(c1)C1(CCCC1)C(O)=O

InChI Key: InChIKey=RMTQEEYHUNGCDX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50417726 (CHEMBL1644212) Show SMILES COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cccc(c1)C1(CCCC1)C(O)=O Show InChI InChI=1S/C25H25Cl2N3O3/c1-33-24-29-21(15-22(30-24)28-12-9-16-7-8-19(26)14-20(16)27)17-5-4-6-18(13-17)25(23(31)32)10-2-3-11-25/h4-8,13-15H,2-3,9-12H2,1H3,(H,31,32)(H,28,29,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.501	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Aventis US Curated by ChEMBL					Assay Description Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...				Bioorg Med Chem Lett 21: 66-75 (2010) Article DOI: 10.1016/j.bmcl.2010.11.071 BindingDB Entry DOI: 10.7270/Q22F7PPM
					More data for this Ligand-Target Pair