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SMILES: NC[C@@H]1CC[C@@H](C1)Oc1ccc2c(cc[nH]c2=O)c1

InChI Key: InChIKey=LANVSAIPMOBGCW-PWSUYJOCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417849   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50417849
PNG
(CHEMBL1667979)
Show SMILES NC[C@@H]1CC[C@@H](C1)Oc1ccc2c(cc[nH]c2=O)c1 |r|
Show InChI InChI=1S/C15H18N2O2/c16-9-10-1-2-12(7-10)19-13-3-4-14-11(8-13)5-6-17-15(14)18/h3-6,8,10,12H,1-2,7,9,16H2,(H,17,18)/t10-,12+/m1/s1
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Similars
Article
PubMed
n/an/a 81.3n/an/an/an/an/an/a



MSD

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 21: 1084-8 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.104
BindingDB Entry DOI: 10.7270/Q2DN468G
More data for this
Ligand-Target Pair