BDBM50418041 CHEMBL1688402::US10851083, Example 1

SMILES: OC(=O)c1cnn(c1)-c1nc2ccccc2[nH]1

InChI Key: InChIKey=MAFPBDKXQKJAPP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (aa 181-417) (Homo sapiens (Human))	BDBM50418041 (CHEMBL1688402 | US10851083, Example 1) Show SMILES OC(=O)c1cnn(c1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H8N4O2/c16-10(17)7-5-12-15(6-7)11-13-8-3-1-2-4-9(8)14-11/h1-6H,(H,13,14)(H,16,17)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020)
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50418041 (CHEMBL1688402 | US10851083, Example 1) Show SMILES OC(=O)c1cnn(c1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C11H8N4O2/c16-10(17)7-5-12-15(6-7)11-13-8-3-1-2-4-9(8)14-11/h1-6H,(H,13,14)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PHD2				ACS Med Chem Lett 1: 526-529 (2010) Article DOI: 10.1021/ml100198y BindingDB Entry DOI: 10.7270/Q28053VF
					More data for this Ligand-Target Pair