BDBM50418069 CHEMBL1688979

SMILES: C(Cn1ccnc1)Cn1cc(CC2CCCCC2)nn1

InChI Key: InChIKey=URLZEOPFRQZBGW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50418069 (CHEMBL1688979) Show SMILES C(Cn1ccnc1)Cn1cc(CC2CCCCC2)nn1 Show InChI InChI=1S/C15H23N5/c1-2-5-14(6-3-1)11-15-12-20(18-17-15)9-4-8-19-10-7-16-13-19/h7,10,12-14H,1-6,8-9,11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 54: 1693-703 (2011) Article DOI: 10.1021/jm1013488 BindingDB Entry DOI: 10.7270/Q20G3MDD
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50418069 (CHEMBL1688979) Show SMILES C(Cn1ccnc1)Cn1cc(CC2CCCCC2)nn1 Show InChI InChI=1S/C15H23N5/c1-2-5-14(6-3-1)11-15-12-20(18-17-15)9-4-8-19-10-7-16-13-19/h7,10,12-14H,1-6,8-9,11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 54: 1693-703 (2011) Article DOI: 10.1021/jm1013488 BindingDB Entry DOI: 10.7270/Q20G3MDD
					More data for this Ligand-Target Pair