Found 4 hits for monomerid = 50418135 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50418135
(CHEMBL1760274)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(c1)C1CCCCC1 Show InChI InChI=1S/C32H38ClNO5S/c1-4-5-20-34(30-13-9-12-28(22(30)2)25-14-16-26(33)17-15-25)40(37,38)27-18-19-31(39-23(3)32(35)36)29(21-27)24-10-7-6-8-11-24/h9,12-19,21,23-24H,4-8,10-11,20H2,1-3H3,(H,35,36) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARgamma by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418135
(CHEMBL1760274)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(c1)C1CCCCC1 Show InChI InChI=1S/C32H38ClNO5S/c1-4-5-20-34(30-13-9-12-28(22(30)2)25-14-16-26(33)17-15-25)40(37,38)27-18-19-31(39-23(3)32(35)36)29(21-27)24-10-7-6-8-11-24/h9,12-19,21,23-24H,4-8,10-11,20H2,1-3H3,(H,35,36) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Partial agonist activity at human PPARdelta expressed in african green monkey CV1 cells transfected with Gal4 assessed as beta-galactosidase activity... |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418135
(CHEMBL1760274)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(c1)C1CCCCC1 Show InChI InChI=1S/C32H38ClNO5S/c1-4-5-20-34(30-13-9-12-28(22(30)2)25-14-16-26(33)17-15-25)40(37,38)27-18-19-31(39-23(3)32(35)36)29(21-27)24-10-7-6-8-11-24/h9,12-19,21,23-24H,4-8,10-11,20H2,1-3H3,(H,35,36) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARdelta by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50418135
(CHEMBL1760274)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)cc1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(c1)C1CCCCC1 Show InChI InChI=1S/C32H38ClNO5S/c1-4-5-20-34(30-13-9-12-28(22(30)2)25-14-16-26(33)17-15-25)40(37,38)27-18-19-31(39-23(3)32(35)36)29(21-27)24-10-7-6-8-11-24/h9,12-19,21,23-24H,4-8,10-11,20H2,1-3H3,(H,35,36) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARalpha by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |