Found 4 hits for monomerid = 50418159 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418159
(CHEMBL1760422)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H31Cl2NO5S/c1-6-7-15-31(25-10-8-9-22(19(25)4)21-11-12-23(29)24(30)16-21)37(34,35)27-14-13-26(17(2)18(27)3)36-20(5)28(32)33/h8-14,16,20H,6-7,15H2,1-5H3,(H,32,33) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Partial agonist activity at human PPARdelta expressed in african green monkey CV1 cells transfected with Gal4 assessed as beta-galactosidase activity... |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50418159
(CHEMBL1760422)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H31Cl2NO5S/c1-6-7-15-31(25-10-8-9-22(19(25)4)21-11-12-23(29)24(30)16-21)37(34,35)27-14-13-26(17(2)18(27)3)36-20(5)28(32)33/h8-14,16,20H,6-7,15H2,1-5H3,(H,32,33) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARalpha by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50418159
(CHEMBL1760422)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H31Cl2NO5S/c1-6-7-15-31(25-10-8-9-22(19(25)4)21-11-12-23(29)24(30)16-21)37(34,35)27-14-13-26(17(2)18(27)3)36-20(5)28(32)33/h8-14,16,20H,6-7,15H2,1-5H3,(H,32,33) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARgamma by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50418159
(CHEMBL1760422)Show SMILES CCCCN(c1cccc(c1C)-c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccc(OC(C)C(O)=O)c(C)c1C Show InChI InChI=1S/C28H31Cl2NO5S/c1-6-7-15-31(25-10-8-9-22(19(25)4)21-11-12-23(29)24(30)16-21)37(34,35)27-14-13-26(17(2)18(27)3)36-20(5)28(32)33/h8-14,16,20H,6-7,15H2,1-5H3,(H,32,33) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of [3H]GW 2433 from human PPARdelta by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2345-50 (2011)
Article DOI: 10.1016/j.bmcl.2011.02.077 BindingDB Entry DOI: 10.7270/Q2M61MHT |
More data for this Ligand-Target Pair | |