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SMILES: COC(=O)c1cccc(c1)C(=O)N1CCC(CCN2C3CCC2CC(C3)n2c(C)nc3ccccc23)(CC1)c1ccccc1

InChI Key: InChIKey=DNHRQMMBAAKVNY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418519   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50418519
PNG
(CHEMBL1784472)
Show SMILES COC(=O)c1cccc(c1)C(=O)N1CCC(CCN2C3CCC2CC(C3)n2c(C)nc3ccccc23)(CC1)c1ccccc1
Show InChI InChI=1S/C37H42N4O3/c1-26-38-33-13-6-7-14-34(33)41(26)32-24-30-15-16-31(25-32)40(30)22-19-37(29-11-4-3-5-12-29)17-20-39(21-18-37)35(42)27-9-8-10-28(23-27)36(43)44-2/h3-14,23,30-32H,15-22,24-25H2,1-2H3
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Similars
Article
PubMed
n/an/a 794n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human Erg by patch clamp assay

J Med Chem 54: 3756-67 (2011)


Article DOI: 10.1021/jm200279v
BindingDB Entry DOI: 10.7270/Q26111K7
More data for this
Ligand-Target Pair