BDBM50419374 CHEMBL1916273

SMILES: CC(C)NC(=O)c1c(C)nn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1

InChI Key: InChIKey=ZHZJHDVPDAOZPP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419374 (CHEMBL1916273) Show SMILES CC(C)NC(=O)c1c(C)nn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1 Show InChI InChI=1S/C21H24N4O3S/c1-14(2)22-21(26)19-16(4)23-25(17-8-6-5-7-9-17)20(19)24-29(27,28)18-12-10-15(3)11-13-18/h5-14,24H,1-4H3,(H,22,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ
					More data for this Ligand-Target Pair