BDBM50419378 CHEMBL1916279

SMILES: Cc1nn(c(NS(=O)(=O)c2ccc(C)cc2)c1C(=O)NCC(C)(C)C)-c1ccccc1

InChI Key: InChIKey=LXYSCROSLDLXCB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419378 (CHEMBL1916279) Show SMILES Cc1nn(c(NS(=O)(=O)c2ccc(C)cc2)c1C(=O)NCC(C)(C)C)-c1ccccc1 Show InChI InChI=1S/C23H28N4O3S/c1-16-11-13-19(14-12-16)31(29,30)26-21-20(22(28)24-15-23(3,4)5)17(2)25-27(21)18-9-7-6-8-10-18/h6-14,26H,15H2,1-5H3,(H,24,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ
					More data for this Ligand-Target Pair