BDBM50419447 CHEMBL1923025

SMILES: CCCCN=C(NC1CCCC1)SCCCc1cnc[nH]1

InChI Key: InChIKey=ZUIOKZVLMBWAPI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50419447 (CHEMBL1923025) Show SMILES CCCCN=C(NC1CCCC1)SCCCc1cnc[nH]1 |w:4.3| Show InChI InChI=1S/C16H28N4S/c1-2-3-10-18-16(20-14-7-4-5-8-14)21-11-6-9-15-12-17-13-19-15/h12-14H,2-11H2,1H3,(H,17,19)(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50419447 (CHEMBL1923025) Show SMILES CCCCN=C(NC1CCCC1)SCCCc1cnc[nH]1 |w:4.3| Show InChI InChI=1S/C16H28N4S/c1-2-3-10-18-16(20-14-7-4-5-8-14)21-11-6-9-15-12-17-13-19-15/h12-14H,2-11H2,1H3,(H,17,19)(H,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair