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SMILES: NC(=O)[C@@H]1CCCN1C(=O)c1ccc(NC(=O)c2ccc(cc2)C#N)cc1

InChI Key: InChIKey=CMRWIQZTSITXKY-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420647   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50420647
PNG
(CHEMBL2086607)
Show SMILES NC(=O)[C@@H]1CCCN1C(=O)c1ccc(NC(=O)c2ccc(cc2)C#N)cc1 |r|
Show InChI InChI=1S/C20H18N4O3/c21-12-13-3-5-14(6-4-13)19(26)23-16-9-7-15(8-10-16)20(27)24-11-1-2-17(24)18(22)25/h3-10,17H,1-2,11H2,(H2,22,25)(H,23,26)/t17-/m0/s1
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MMDB

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Article
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n/an/a 34n/an/an/an/an/an/a



Zydus Research Centre

Curated by ChEMBL


Assay Description
Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assay

Bioorg Med Chem Lett 22: 3516-21 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.078
BindingDB Entry DOI: 10.7270/Q2QZ2C77
More data for this
Ligand-Target Pair