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SMILES: FC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=VNLAQYMGUSCAEB-ZDUSSCGKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420652   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50420652
PNG
(CHEMBL2086612)
Show SMILES FC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N1CCC[C@H]1C#N |r|
Show InChI InChI=1S/C16H16F3N3O2/c17-16(18,19)12-5-3-11(4-6-12)15(24)21-8-7-14(23)22-9-1-2-13(22)10-20/h3-6,13H,1-2,7-9H2,(H,21,24)/t13-/m0/s1
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PubMed
n/an/a 13.2n/an/an/an/an/an/a



Zydus Research Centre

Curated by ChEMBL


Assay Description
Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assay

Bioorg Med Chem Lett 22: 3516-21 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.078
BindingDB Entry DOI: 10.7270/Q2QZ2C77
More data for this
Ligand-Target Pair