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SMILES: O=C(Nc1ccc(cc1)C(=O)N1CCC[C@H]1C#N)c1ccc(cc1)C#N

InChI Key: InChIKey=KBEVPPOZVXVLEU-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420654   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50420654
PNG
(CHEMBL2086615)
Show SMILES O=C(Nc1ccc(cc1)C(=O)N1CCC[C@H]1C#N)c1ccc(cc1)C#N |r|
Show InChI InChI=1S/C20H16N4O2/c21-12-14-3-5-15(6-4-14)19(25)23-17-9-7-16(8-10-17)20(26)24-11-1-2-18(24)13-22/h3-10,18H,1-2,11H2,(H,23,25)/t18-/m0/s1
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MMDB

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Article
PubMed
n/an/a 11.6n/an/an/an/an/an/a



Zydus Research Centre

Curated by ChEMBL


Assay Description
Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assay

Bioorg Med Chem Lett 22: 3516-21 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.078
BindingDB Entry DOI: 10.7270/Q2QZ2C77
More data for this
Ligand-Target Pair