BDBM50421157 CHEMBL2088608

SMILES: Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12

InChI Key: InChIKey=SQGNWPWTSKHMHD-GXDHUFHOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase (Bos taurus (Bovine))	BDBM50421157 (CHEMBL2088608) Show SMILES Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12 Show InChI InChI=1S/C26H22N2O2/c1-28-23-8-3-2-7-21(23)22-15-17(9-13-24(22)28)10-14-25(29)19-5-4-6-20(16-19)27-26(30)18-11-12-18/h2-10,13-16,18H,11-12H2,1H3,(H,27,30)/b14-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of bovine milk XO assessed as decrease in uric acid formation after 5 mins by UV-spectrophotometric analysis				Bioorg Med Chem 20: 5649-57 (2012) Article DOI: 10.1016/j.bmc.2012.07.001 BindingDB Entry DOI: 10.7270/Q24X5934
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50421157 (CHEMBL2088608) Show SMILES Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12 Show InChI InChI=1S/C26H22N2O2/c1-28-23-8-3-2-7-21(23)22-15-17(9-13-24(22)28)10-14-25(29)19-5-4-6-20(16-19)27-26(30)18-11-12-18/h2-10,13-16,18H,11-12H2,1H3,(H,27,30)/b14-10+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-DOPA as substrate after 5 mins by UV-spectrophotometric analysis				Bioorg Med Chem 20: 5649-57 (2012) Article DOI: 10.1016/j.bmc.2012.07.001 BindingDB Entry DOI: 10.7270/Q24X5934
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50421157 (CHEMBL2088608) Show SMILES Cn1c2ccccc2c2cc(\C=C\C(=O)c3cccc(NC(=O)C4CC4)c3)ccc12 Show InChI InChI=1S/C26H22N2O2/c1-28-23-8-3-2-7-21(23)22-15-17(9-13-24(22)28)10-14-25(29)19-5-4-6-20(16-19)27-26(30)18-11-12-18/h2-10,13-16,18H,11-12H2,1H3,(H,27,30)/b14-10+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Solapur University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 5 mins by UV-spectrophotometric analysis				Bioorg Med Chem 20: 5649-57 (2012) Article DOI: 10.1016/j.bmc.2012.07.001 BindingDB Entry DOI: 10.7270/Q24X5934
					More data for this Ligand-Target Pair