BDBM50421231 CHEMBL2087646
SMILES: NCCSc1nc2ccccc2o1
InChI Key: InChIKey=LIZDKHZOMRDDRY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50421231 (CHEMBL2087646) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | 646 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gedeon Richter Plc., Gy�mroi�t 19-21, Budapest H-1103, Hungary. Curated by ChEMBL | Assay Description Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun... | Bioorg Med Chem 23: 3991-9 (2015) Article DOI: 10.1016/j.bmc.2015.01.013 BindingDB Entry DOI: 10.7270/Q2GM892T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimethylarginine dimethylaminohydrolase 1 (DDAH) (Homo sapiens (Human)) | BDBM50421231 (CHEMBL2087646) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | 1.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs... | Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimethylarginine dimethylaminohydrolase 1 (DDAH) (Homo sapiens (Human)) | BDBM50421231 (CHEMBL2087646) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Texas Curated by ChEMBL | Assay Description Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ... | Bioorg Med Chem 20: 5550-8 (2012) Article DOI: 10.1016/j.bmc.2012.07.022 BindingDB Entry DOI: 10.7270/Q2416ZBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50421231 (CHEMBL2087646) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a |
Gedeon Richter Plc., Gy�mroi�t 19-21, Budapest H-1103, Hungary. Curated by ChEMBL | Assay Description Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca... | Bioorg Med Chem 23: 3991-9 (2015) Article DOI: 10.1016/j.bmc.2015.01.013 BindingDB Entry DOI: 10.7270/Q2GM892T | |||||||||||
More data for this Ligand-Target Pair |