BDBM50421604 ACH-126443::ELVUCITABINE

SMILES: Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1

InChI Key: InChIKey=HSBKFSPNDWWPSL-VDTYLAMSSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50421604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50421604 (ACH-126443 | ELVUCITABINE) Show SMILES Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1 |c:15| Show InChI InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutant				Bioorg Med Chem Lett 13: 1993-6 (2003) BindingDB Entry DOI: 10.7270/Q2639Q86
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50421604 (ACH-126443 | ELVUCITABINE) Show SMILES Nc1nc(=O)n(cc1F)[C@H]1O[C@@H](CO)C=C1 |c:15| Show InChI InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description In vitro antiviral activity against HIV-1 Reverse transcriptase wild type				Bioorg Med Chem Lett 13: 1993-6 (2003) BindingDB Entry DOI: 10.7270/Q2639Q86
					More data for this Ligand-Target Pair