BDBM50421897 CHEMBL545689

SMILES: C(N1CC[C@@H]2[C@@H](CCc3ccccc23)C1)c1ccco1

InChI Key: InChIKey=HTNSCWCPUAQWFB-MAUKXSAKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50421897 (CHEMBL545689) Show SMILES C(N1CC[C@@H]2[C@@H](CCc3ccccc23)C1)c1ccco1 |r| Show InChI InChI=1S/C18H21NO/c1-2-6-17-14(4-1)7-8-15-12-19(10-9-18(15)17)13-16-5-3-11-20-16/h1-6,11,15,18H,7-10,12-13H2/t15-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum				J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8
					More data for this Ligand-Target Pair