BDBM50422424 CHEMBL4170719

SMILES: CN(C(=O)c1ccc(F)c(O)c1)c1cccc(n1)-c1cccc(O)c1F

InChI Key: InChIKey=KAQXAXYRODEDPU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50422424 (CHEMBL4170719) Show SMILES CN(C(=O)c1ccc(F)c(O)c1)c1cccc(n1)-c1cccc(O)c1F Show InChI InChI=1S/C42H76N6O2/c1-49-41-25-13-11-23-39(41)37-47-35-21-33-45-31-19-9-7-17-29-43-27-15-5-3-4-6-16-28-44-30-18-8-10-20-32-46-34-22-36-48-38-40-24-12-14-26-42(40)50-2/h11-14,23-26,43-48H,3-10,15-22,27-38H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NA...				Eur J Med Chem 155: 61-76 (2018) Article DOI: 10.1016/j.ejmech.2018.05.029 BindingDB Entry DOI: 10.7270/Q23F4S76
					More data for this Ligand-Target Pair