BDBM50422427 CHEMBL4177499

SMILES: Oc1cc(Nc2cccc(n2)-c2cccc(O)c2F)ccc1F

InChI Key: InChIKey=WBGAUAWHOHYUQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50422427 (CHEMBL4177499) Show SMILES Oc1cc(Nc2cccc(n2)-c2cccc(O)c2F)ccc1F Show InChI InChI=1S/C44H62N4O2/c1-49-43-19-13-11-17-41(43)35-47-33-39-25-21-37(22-26-39)31-45-29-15-9-7-5-3-4-6-8-10-16-30-46-32-38-23-27-40(28-24-38)34-48-36-42-18-12-14-20-44(42)50-2/h11-14,17-28,45-48H,3-10,15-16,29-36H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Binding affinity to recombinant 17beta-HSD14 (unknown origin) expressed in Escherichia coli BL21 pLysS strain using E2 as substrate in presence of NA...				Eur J Med Chem 155: 61-76 (2018) Article DOI: 10.1016/j.ejmech.2018.05.029 BindingDB Entry DOI: 10.7270/Q23F4S76
					More data for this Ligand-Target Pair