BDBM50422693 CHEMBL433964::RU-846

SMILES: CC#C[C@]1(O)CCC2C3CCC4CC(=O)CCC4=C3C(C[C@]12C)c1ccc(cc1)N(C)C

InChI Key: InChIKey=CBRSQISSOYDHQA-OYPKFWCBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50422693 (CHEMBL433964 | RU-846) Show SMILES CC#C[C@]1(O)CCC2C3CCC4CC(=O)CCC4=C3C(C[C@]12C)c1ccc(cc1)N(C)C |c:18| Show InChI InChI=1S/C29H37NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,20,24-26,32H,8,11-14,16-18H2,1-4H3/t20?,24?,25?,26?,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity for Glucocorticoid receptor in MMTV transactivation assay in human A549 lung epithelial cells at 10 uM				J Med Chem 48: 4507-10 (2005) Article DOI: 10.1021/jm050345y BindingDB Entry DOI: 10.7270/Q2T43VCV
					More data for this Ligand-Target Pair