BDBM50422720 CHEMBL177705

SMILES: FC(F)(F)Oc1ccc(Cn2c(=O)c3c(c2=O)c(=O)c2[nH]cc[nH]c2c3=O)cc1

InChI Key: InChIKey=BWUBRJUNRNTIBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50422720 (CHEMBL177705) Show SMILES FC(F)(F)Oc1ccc(Cn2c(=O)c3c(c2=O)c(=O)c2[nH]cc[nH]c2c3=O)cc1 Show InChI InChI=1S/C18H10F3N3O5/c19-18(20,21)29-9-3-1-8(2-4-9)7-24-16(27)10-11(17(24)28)15(26)13-12(14(10)25)22-5-6-23-13/h1-6,22-23H,7H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tibotec BVBA Curated by ChEMBL					Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase				J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ
					More data for this Ligand-Target Pair