BDBM50423220 CHEMBL240000

SMILES: CCC1CCCCN1C[C@@H](O)CNS(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=KMHBKDJSYQLVTR-ZVAWYAOSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50423220 (CHEMBL240000) Show SMILES CCC1CCCCN1C[C@@H](O)CNS(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C20H28N2O3S/c1-2-17-10-5-6-13-22(17)15-18(23)14-21-26(24,25)20-12-7-9-16-8-3-4-11-19(16)20/h3-4,7-9,11-12,17-18,21,23H,2,5-6,10,13-15H2,1H3/t17?,18-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells				Bioorg Med Chem Lett 17: 1741-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.063 BindingDB Entry DOI: 10.7270/Q29W0GSG
					More data for this Ligand-Target Pair