BDBM50423223 CHEMBL239812

SMILES: O[C@@H](CNS(=O)(=O)c1cccc2ccccc12)CN1CCCC1C1CC1

InChI Key: InChIKey=JMVRBNGGLNYRTP-KKFHFHRHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50423223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50423223 (CHEMBL239812) Show SMILES O[C@@H](CNS(=O)(=O)c1cccc2ccccc12)CN1CCCC1C1CC1 Show InChI InChI=1S/C20H26N2O3S/c23-17(14-22-12-4-8-19(22)16-10-11-16)13-21-26(24,25)20-9-3-6-15-5-1-2-7-18(15)20/h1-3,5-7,9,16-17,19,21,23H,4,8,10-14H2/t17-,19?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells				Bioorg Med Chem Lett 17: 1741-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.063 BindingDB Entry DOI: 10.7270/Q29W0GSG
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM50423223 (CHEMBL239812) Show SMILES O[C@@H](CNS(=O)(=O)c1cccc2ccccc12)CN1CCCC1C1CC1 Show InChI InChI=1S/C20H26N2O3S/c23-17(14-22-12-4-8-19(22)16-10-11-16)13-21-26(24,25)20-9-3-6-15-5-1-2-7-18(15)20/h1-3,5-7,9,16-17,19,21,23H,4,8,10-14H2/t17-,19?/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells				Bioorg Med Chem Lett 17: 1741-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.063 BindingDB Entry DOI: 10.7270/Q29W0GSG
					More data for this Ligand-Target Pair