BDBM50423233 CHEMBL240042

SMILES: CC1CC(C)N(C[C@@H](O)CNS(=O)(=O)c2cc(Cl)sc2Cl)C1

InChI Key: InChIKey=MPFZBFNQYBYBCS-RTBKNWGFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50423233 (CHEMBL240042) Show SMILES CC1CC(C)N(C[C@@H](O)CNS(=O)(=O)c2cc(Cl)sc2Cl)C1 Show InChI InChI=1S/C13H20Cl2N2O3S2/c1-8-3-9(2)17(6-8)7-10(18)5-16-22(19,20)11-4-12(14)21-13(11)15/h4,8-10,16,18H,3,5-7H2,1-2H3/t8?,9?,10-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells				Bioorg Med Chem Lett 17: 1741-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.063 BindingDB Entry DOI: 10.7270/Q29W0GSG
					More data for this Ligand-Target Pair