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BDBM50423242 CHEMBL240032

SMILES: CC1CC(C)N(C[C@@H](O)CNS(=O)(=O)c2ccc3ccccc3c2)C1

InChI Key: InChIKey=XTEIDNBHYNANFK-JMLCCBQJSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423242   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50423242
PNG
(CHEMBL240032)
Show SMILES CC1CC(C)N(C[C@@H](O)CNS(=O)(=O)c2ccc3ccccc3c2)C1
Show InChI InChI=1S/C19H26N2O3S/c1-14-9-15(2)21(12-14)13-18(22)11-20-25(23,24)19-8-7-16-5-3-4-6-17(16)10-19/h3-8,10,14-15,18,20,22H,9,11-13H2,1-2H3/t14?,15?,18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells


Bioorg Med Chem Lett 17: 1741-5 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.063
BindingDB Entry DOI: 10.7270/Q29W0GSG
More data for this
Ligand-Target Pair