BDBM50423243 CHEMBL240225

SMILES: CCc1cc(Br)ccc1S(=O)(=O)NC[C@H](O)CN1CC(C)CC1C

InChI Key: InChIKey=KAXSUUHPVKUEOE-ZUEPYMLJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423243   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM50423243 (CHEMBL240225) Show SMILES CCc1cc(Br)ccc1S(=O)(=O)NC[C@H](O)CN1CC(C)CC1C Show InChI InChI=1S/C17H27BrN2O3S/c1-4-14-8-15(18)5-6-17(14)24(22,23)19-9-16(21)11-20-10-12(2)7-13(20)3/h5-6,8,12-13,16,19,21H,4,7,9-11H2,1-3H3/t12?,13?,16-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake in human GlyT1c expressed in HEK293 cells				Bioorg Med Chem Lett 17: 1741-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.063 BindingDB Entry DOI: 10.7270/Q29W0GSG
					More data for this Ligand-Target Pair