BDBM50423716 CHEMBL606865

SMILES: [O-][N+](=O)c1ccc2[c-](C3=[NH+]c4ccc(Br)cc4C3=O)c(=O)[nH]c2c1

InChI Key: InChIKey=YGMDRWHLKOMUQX-UHFFFAOYSA-O

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50423716 (CHEMBL606865) Show SMILES [O-][N+](=O)c1ccc2[c-](C3=[NH+]c4ccc(Br)cc4C3=O)c(=O)[nH]c2c1 |t:8| Show InChI InChI=1S/C16H7BrN3O4/c17-7-1-4-11-10(5-7)15(21)14(18-11)13-9-3-2-8(20(23)24)6-12(9)19-16(13)22/h1-6H,(H,19,22)/q-1/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de La Rochelle Curated by ChEMBL					Assay Description Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation counting				Bioorg Med Chem 17: 6257-63 (2009) Article DOI: 10.1016/j.bmc.2009.07.051 BindingDB Entry DOI: 10.7270/Q2BR8S9W
					More data for this Ligand-Target Pair